CureARS

Mitochondrial (mt) Aminoacyl tRNA Synthetase (ARS) genes are essential for the cells in the body to make energy within the mitochondria. Inherited mutations in these genes cause ultra-rare types of Mitochondrial Disease (Mito). Just as there are different types of cancers, there are many different types of Mitochondrial Disease. There are over 300 genes that cause different types of Mito, and there are 20 Mito ARS genes.